Training Program in Developmental Biology (T32 HD055164)

Program DirectorVictoria Prince

Administrator: Kristine Gaston
Phone: 2-8037
Fax: 2-3172

Openings: 4 Predoctoral, 0 Postdoctoral

The core mission of the developmental biology training program (DBTP) is to train students to analyze all aspects of developmental processes from a broad interdisciplinary perspective, integrating cellular, molecular and genetic approaches. Developmental Biology is by its nature a highly integrative discipline that takes multiple approaches to study a range of topics including embryogenesis, organogenesis, cell fate specification, stem cell biology, cancer and regeneration. Studies in these areas have major impact on biomedical research and training: developmental biologists have been instrumental in developing animal models of human disease and experimental systems to allow rigorous studies of genetic mechanisms in whole animals. At Chicago our developmental biologists are using an array of experimental approaches to address a wide range of questions across the entire spectrum of developmental model systems, as well as using comparative approaches in non-model systems. We can thus offer our trainees a uniquely diverse training experience that prepares them for careers in advanced research and education.

Training Faculty:

  • Prince, Victoria: Regionalization of the vertebrate anterior-posterior axis, using zebrafish as a model
  • Carrillo, Robert: Drosophila developmental neurobiology
  • deJong, Jill: Hematopoietic stem cell transplant, cancer and blood diseases
  • Du, Wei: Cell cycle, tumor suppressor genes and development
  • Fehon, Richard: Regulation of epithelial polarity and proliferation during development
  • Ferguson, Edwin: Developmental genetics of cell fate specification and stem cell maintenance in Drosophila
  • Gilad, Yoav: Understanding gene regulatory processes and elucidating the genetic architecture of human-specific traits including disease
  • Glotzer, Michael: The molecular mechanism of cytokinesis in animal cells
  • Green, William: Cell biology of neurotransmitter receptors
  • Grove, Elizabeth: Cellular and molecular mechanisms that control patterning, cell fate choice, and differentiation in the mammalian forebrain
  • Heckscher, Ellie: Development and function of neural circuits in the motor system
  • Ho, Robert: Pattern formation and early development in the simple vertebrate zebrafish
  • Horne-Badovinac, Sally: Epithelial morphogenesis and organ shape
  • Kee, Barbara: Transcriptional regulation of lymphocyte development
  • Kovar, David: Biochemical mechanisms of actin filament assembly
  • Kratsios, Paschalis: Molecular principles governing motor neuron diversity and motor circuit assembly​
  • Kreitman, Martin: Functional evolution of cisregulatory sequences, and canalization in evolution and development
  • Kronforst, Marcus: Evolution and genetics of adaptation and speciation with butterflies as the primary model system
  • Lahn, Bruce: Epigenetic mechanisms of cell fate restriction in stem cell differentiation
  • Lynch, Vincent: Functional and evolutionary genomics approaches to understand how gene regulatory changes during development led to the origin of mammalian pregnancy and neocortical expansion in the human lineage
  • Macleod, Kay: Regulation of cell cycle checkpoints and cell death in response to oxidative stress and DNA damage
  • Malamy, Jocelyn: Molecular regulation of root system growth and development; establishing drought tolerance in crop plants
  • Moskowitz, Ivan: Molecular genetics of cardiovascular development and congenital heart disease
  • Munro, Edwin: Actomyosin network dynamics and contractility; cell polarization; tissue morphogenesis; computational cell and developmental biology
  • Ragsdale, Cliff: Molecular and cellular mechanisms of brain development
  • Rebay, Ilaria: Transcriptional regulatory circuitries in development and disease; Receptor tyrosine kinase signal transduction
  • Reinitz, John: Systems approaches to the establishment of biological form
  • Rust, Michael: Molecular investigations small networks including those underlying circadian clocks
  • Schmidt-Ott, Urs: Developmental genetics and evolution of insects
  • Schwartz, Nancy: Transcriptional control of ECM expression during chondrogenesis and neurogenesis; regulation of sulfate activation; skeletal dysplasias
  • Shubin, Neil: Paleontology and developmental studies in salamanders to identify mechanisms behind the evolutionary origin of new anatomical features and faunas
  • Wei, Wei: Development and function of the neural circuits in the retina
  • Wu, Xiaoyang: Role of cytoskeletal dynamics in transmitting niche signals to regulate skin somatic stem cell activity and functions
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