Publications

Dimerization and dynamics of angiotensin-I converting enzyme revealed by cryoEM and MD simulations.

Mancl JM, Wu X, Zhao M, Tang WJ

Dimerization and dynamics of angiotensin-I converting enzyme revealed by cryoEM and MD simulations. bioRxiv. 2025 Jan 19.

PMID: 39868314

Structural studies of the IFN?4 receptor complex using cryoEM enabled by protein engineering.

Grubbe WS, Zhang B, Kauffman A, Byléhn F, Padol K, Jung HG, Park SB, Priest JM, Özkan E, de Pablo JJ, Liang TJ, Zhao M, Mendoza JL

Structural studies of the IFN?4 receptor complex using cryoEM enabled by protein engineering. Nat Commun. 2025 Jan 18; 16(1):818.

PMID: 39827213

PTPN2 copper-sensing relays copper level fluctuations into EGFR/CREB activation and associated CTR1 transcriptional repression.

Ross MO, Xie Y, Owyang RC, Ye C, Zbihley ONP, Lyu R, Wu T, Wang P, Karginova O, Olopade OI, Zhao M, He C

PTPN2 copper-sensing relays copper level fluctuations into EGFR/CREB activation and associated CTR1 transcriptional repression. Nat Commun. 2024 Aug 13; 15(1):6947.

PMID: 39138174

Author Correction: An engineered hypercompact CRISPR-Cas12f system with boosted gene-editing activity.

Wu T, Liu C, Zou S, Lyu R, Yang B, Yan H, Zhao M, Tang W

Author Correction: An engineered hypercompact CRISPR-Cas12f system with boosted gene-editing activity. Nat Chem Biol. 2024 Jan; 20(1):129.

PMID: 38040979

Author Correction: An engineered hypercompact CRISPR-Cas12f system with boosted gene-editing activity.

Wu T, Liu C, Zou S, Lyu R, Yang B, Yan H, Zhao M, Tang W

Author Correction: An engineered hypercompact CRISPR-Cas12f system with boosted gene-editing activity. Nat Chem Biol. 2023 Dec 01.

PMID: 38040979

An engineered hypercompact CRISPR-Cas12f system with boosted gene-editing activity.

Wu T, Liu C, Zou S, Lyu R, Yang B, Yan H, Zhao M, Tang W

An engineered hypercompact CRISPR-Cas12f system with boosted gene-editing activity. Nat Chem Biol. 2023 Nov; 19(11):1384-1393.

PMID: 37400536

CAND1 orchestrates CRLs through rock and roll.

Xie Y, Zhao M

CAND1 orchestrates CRLs through rock and roll. Cell. 2023 04 27; 186(9):1817-1818.

PMID: 37116466

A novel membrane complex is required for docking and regulated exocytosis of lysosome-related organelles in Tetrahymena thermophila.

Kuppannan A, Jiang YY, Maier W, Liu C, Lang CF, Cheng CY, Field MC, Zhao M, Zoltner M, Turkewitz AP

A novel membrane complex is required for docking and regulated exocytosis of lysosome-related organelles in Tetrahymena thermophila. PLoS Genet. 2022 05; 18(5):e1010194.

PMID: 35587496

Structural basis for the mechanisms of human presequence protease conformational switch and substrate recognition.

Liang WG, Wijaya J, Wei H, Noble AJ, Mancl JM, Mo S, Lee D, Lin King JV, Pan M, Liu C, Koehler CM, Zhao M, Potter CS, Carragher B, Li S, Tang WJ

Structural basis for the mechanisms of human presequence protease conformational switch and substrate recognition. Nat Commun. 2022 04 05; 13(1):1833.

PMID: 35383169

Structural insights into Ubr1-mediated N-degron polyubiquitination.

Pan M, Zheng Q, Wang T, Liang L, Mao J, Zuo C, Ding R, Ai H, Xie Y, Si D, Yu Y, Liu L, Zhao M

Structural insights into Ubr1-mediated N-degron polyubiquitination. Nature. 2021 12; 600(7888):334-338.

PMID: 34789879