My research is focused on understanding how local brain circuit physiology is impacted by changes in blood gas homeostasis. We study the hippocampus, a brain region important to learning and memory, and brainstem networks involved cardio-respiratory control.
The University of Chicago
Chicago, Illinois
Postdoctoral Fellowship - Neuroscience
2009Wright State University
Dayton, Ohio
Ph.D. - Biomedical Science
2006The Ohio State University
Columbus, Ohio
B.Sc. - Biological Science
1999Metabolic trade-offs in Neonatal sepsis triggered by TLR4 and TLR1/2 ligands result in unique dysfunctions in neural breathing circuits.
Metabolic trade-offs in Neonatal sepsis triggered by TLR4 and TLR1/2 ligands result in unique dysfunctions in neural breathing circuits. Brain Behav Immun. 2024 Jul; 119:333-350.
PMID: 38561095Dynamin-related protein 1 is a critical regulator of mitochondrial calcium homeostasis during myocardial ischemia/reperfusion injury.
Dynamin-related protein 1 is a critical regulator of mitochondrial calcium homeostasis during myocardial ischemia/reperfusion injury. FASEB J. 2024 01; 38(1):e23379.
PMID: 38133921A consequence of immature breathing induces persistent changes in hippocampal synaptic plasticity and behavior: a role of prooxidant state and NMDA receptor imbalance.
A consequence of immature breathing induces persistent changes in hippocampal synaptic plasticity and behavior: a role of prooxidant state and NMDA receptor imbalance. Front Mol Neurosci. 2023; 16:1192833.
PMID: 37456523A Consequence of Immature Breathing induces Persistent Changes in Hippocampal Synaptic Plasticity and Behavior: A Role of Pro-Oxidant State and NMDA Receptor Imbalance.
A Consequence of Immature Breathing induces Persistent Changes in Hippocampal Synaptic Plasticity and Behavior: A Role of Pro-Oxidant State and NMDA Receptor Imbalance. bioRxiv. 2023 Mar 21.
PMID: 36993632Gasotransmitter modulation of hypoglossal motoneuron activity.
Gasotransmitter modulation of hypoglossal motoneuron activity. Elife. 2023 01 19; 12.
PMID: 36656752Performance Characteristics of a Novel 3D-Printed Bubble Intermittent Mandatory Ventilator (B-IMV) for Adult Pulmonary Support.
Performance Characteristics of a Novel 3D-Printed Bubble Intermittent Mandatory Ventilator (B-IMV) for Adult Pulmonary Support. Bioengineering (Basel). 2022 Apr 02; 9(4).
PMID: 35447711Developmental defects and impaired network excitability in a cerebral organoid model of KCNJ11 p.V59M-related neonatal diabetes.
Developmental defects and impaired network excitability in a cerebral organoid model of KCNJ11 p.V59M-related neonatal diabetes. Sci Rep. 2021 11 03; 11(1):21590.
PMID: 34732776Microglial Activation and Neurological Outcomes in a Murine Model of Cardiac Arrest.
Microglial Activation and Neurological Outcomes in a Murine Model of Cardiac Arrest. Neurocrit Care. 2022 02; 36(1):61-70.
PMID: 34268646Intermittent Hypoxia causes targeted disruption to NMDA receptor dependent synaptic plasticity in area CA1 of the hippocampus.
Intermittent Hypoxia causes targeted disruption to NMDA receptor dependent synaptic plasticity in area CA1 of the hippocampus. Exp Neurol. 2021 10; 344:113808.
PMID: 34256046Machine learning-based data analytic approaches for evaluating post-natal mouse respiratory physiological evolution.
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Machine learning-based data analytic approaches for evaluating post-natal mouse respiratory physiological evolution. Respir Physiol Neurobiol. 2021 01; 283:103558.
PMID: 33010456