Bryan Dickinson

Discovery of Thioether-Cyclized Macrocyclic Covalent Inhibitors by mRNA Display.
Discovery of Thioether-Cyclized Macrocyclic Covalent Inhibitors by mRNA Display. J Am Chem Soc. 2024 Aug 28; 146(34):24053-24060.
PMID: 39136646

Palmitoylation at a conserved cysteine residue facilitates gasdermin D-mediated pyroptosis and cytokine release.
Palmitoylation at a conserved cysteine residue facilitates gasdermin D-mediated pyroptosis and cytokine release. Proc Natl Acad Sci U S A. 2024 Jul 16; 121(29):e2400883121.
PMID: 38980908

Development of Luminescent Biosensors for Calprotectin.
Development of Luminescent Biosensors for Calprotectin. ACS Chem Biol. 2024 Jun 21; 19(6):1250-1259.
PMID: 38843544

Bump-hole ZDHHCs.
Bump-hole ZDHHCs. Nat Chem Biol. 2024 Jun; 20(6):666-667.
PMID: 38806775

Expanding RNA editing toolkit using an IDR-based strategy.
Expanding RNA editing toolkit using an IDR-based strategy. Mol Ther Nucleic Acids. 2024 Jun 11; 35(2):102190.
PMID: 38721279

Bioorthogonal masked acylating agents for proximity-dependent RNA labelling.
Bioorthogonal masked acylating agents for proximity-dependent RNA labelling. Nat Chem. 2024 May; 16(5):717-726.
PMID: 38594368

Mechanisms and functions of protein S-acylation.
Mechanisms and functions of protein S-acylation. Nat Rev Mol Cell Biol. 2024 Jun; 25(6):488-509.
PMID: 38355760

Fear extinction is regulated by the activity of long noncoding RNAs at the synapse.
Fear extinction is regulated by the activity of long noncoding RNAs at the synapse. Nat Commun. 2023 Nov 22; 14(1):7616.
PMID: 37993455

RNA-based translation activators for targeted gene upregulation.
RNA-based translation activators for targeted gene upregulation. Nat Commun. 2023 10 26; 14(1):6827.
PMID: 37884512

Regulation of ERK2 activity by dynamic S-acylation.
Regulation of ERK2 activity by dynamic S-acylation. Cell Rep. 2023 09 26; 42(9):113135.
PMID: 37715953

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