Francesca Luca, PhD

Age, stress, and markers of inflammation among middle-aged to older African American adults: Findings from The Heart of Detroit Study.
Age, stress, and markers of inflammation among middle-aged to older African American adults: Findings from The Heart of Detroit Study. Brain Behav Immun. 2026 Aug; 136:106559.
PMID: 41887541

fastdemux: Robust SNP-based demultiplexing of single-cell population genomics data.
fastdemux: Robust SNP-based demultiplexing of single-cell population genomics data. bioRxiv. 2026 Feb 11.
PMID: 41726916

Host genotypes interact with microbial communities to modulate gene expression in the human intestine.
Host genotypes interact with microbial communities to modulate gene expression in the human intestine. medRxiv. 2026 Feb 06.
PMID: 41674640

Metabolic modeling and functional genomics reveal taxa and host gene interactions in colorectal cancer.
Metabolic modeling and functional genomics reveal taxa and host gene interactions in colorectal cancer. bioRxiv. 2026 Jan 28.
PMID: 41659628

Sex-specific associations between loneliness and hair cortisol among older African American adults.
Sex-specific associations between loneliness and hair cortisol among older African American adults. Psychoneuroendocrinology. 2026 Apr; 186:107755.
PMID: 41539174

Host transcriptional responses to gut microbiome variation arising from urbanism.
Host transcriptional responses to gut microbiome variation arising from urbanism. bioRxiv. 2025 Oct 26.
PMID: 41278623

Psychological stress and social support are associated with opposing single-cell pro-inflammatory gene regulatory mechanisms in adults.
Psychological stress and social support are associated with opposing single-cell pro-inflammatory gene regulatory mechanisms in adults. bioRxiv. 2025 Oct 15.
PMID: 41278935

The acute myeloid leukemia microenvironment impairs neutrophil maturation and function through NF-?B signaling.
The acute myeloid leukemia microenvironment impairs neutrophil maturation and function through NF-?B signaling. Blood. 2025 Oct 02; 146(14):1707-1721.
PMID: 40663784

Living in poverty is associated with gene expression changes in immune cells.
Living in poverty is associated with gene expression changes in immune cells. Genetics. 2025 07 09; 230(3).
PMID: 40211598

Chronic inflammation deters natural killer cell fitness and cytotoxicity in myeloid leukemia.
Chronic inflammation deters natural killer cell fitness and cytotoxicity in myeloid leukemia. Blood Adv. 2025 Feb 25; 9(4):759-773.
PMID: 39571169

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