Training Grants

MCB Publications

T32GM144292

Kordon SP, Dutka P, Adamska JM, Bandekar SJ, Leon K, Erramilli SK, Adams B, Li J, Kossiakoff AA and Araç D, 2023, Isoform- and ligand-specific modulation of the adhesion GPCR ADGRL3/Latrophilin3 by a synthetic binder., Nature communications, 14:635 

Hoover A, Sheng X, Gao J, Lee J, Liue H, Taubman B, Suman S, Chen S, Zhao Y, Wu X, 2026. A proteomic atlas of organelle remodeling identifies lysosomal SNX3 as a regulator of Notch signaling in epidermal differentiation. bioRxiv 2026.05.20.726558 [Preprint] 

Wu W, Zhang J, Qu X, Chen T, Li J, Yang Y, Chen L, Hoover A, Guo F, Kong C, Bao B, Lin Q, Zhou M, Zhu L, Wu X and Ma Y, 2025, Enabling Targeted Drug Delivery for Treatment of Ulcerative Colitis with Mucosal-Adhesive Photoreactive Hydrogel., Advanced science (Weinheim, Baden-Wurttemberg, Germany), 12:e2404836 

Zhang J, Pan T, Lee J, Goldberg S, King SA, Tang E, Hu Y, Chen L, Hoover A, Zhu L, Eng OS, Dekel B, Huang J and Wu X, 2025, Enabling tumor-specific drug delivery by targeting the Warburg effect of cancer., Cell reports. Medicine, 6:101920 

Liu H, Su P, Li Y, Hoover A, Hu S, King SA, Zhao J, Guan JL, Chen SY, Zhao Y, Tan M and Wu X, 2024, VAMP2 controls murine epidermal differentiation and carcinogenesis by regulation of nucleophagy., Developmental cell, 59:20052016.e4 

Zhang J, Zheng Y, Lee J, Hoover A, King SA, Chen L, Zhao J, Lin Q, Yu C, Zhu L and Wu X, 2023, Continuous Glucose Monitoring Enabled by Fluorescent Nanodiamond Boronic Hydrogel., Advanced science (Weinheim, Baden-Wurttemberg, Germany), 10:e2203943 

Slezak T, O'Leary KM, Guevara Avella T, Musial N, Li J, Andrzejczak A, Scott EF, Le DA and Kossiakoff AA, 2026, Dynamic translocation of Inside-Out proteins to the cell surface underlies cellular adaptation to cancer-induced stress., Proceedings of the National Academy of Sciences of the United States of America, 123:e2529493123 

Slezak T, O'Leary KM, Li J, Rohaim A, Davydova EK and Kossiakoff AA, 2025, Engineered protein G variants for multifunctional antibody-based assemblies., Protein science:a publication of the Protein Society, 34:e70019 

O'Leary KM, Slezak T and Kossiakoff AA, 2025, Conformation-specific synthetic intrabodies modulate mTOR signaling with subcellular spatial resolution., Proceedings of the National Academy of Sciences of the United States of America, 122:e2424679122

O'Leary, Kelly Kossiakoff, Anthony A Past 2020-2025 Slezak T, O'Leary KM, Li J, Rohaim A, Davydova EK and Kossiakoff AA, 2024, Engineered Protein-G variants for plug-and-play applications. bioRxiv 606809 [Preprint]

Chowdhary S, Paracha S, Dyer L and Pincus D, 2025, Emergent 3D genome reorganization from the stepwise assembly of transcriptional condensates., bioRxiv 639564 [Preprint] 

Dea A, Lan Y, Doran BA, Ali A, Igarashi MG, Dyer L, Aksianiuk V, Pincus D, Raman AS. 2026 Physiological architecture and evolutionary origins of cellular adaptability. bioRxiv 717775 [Preprint]. 

Chakraborty P, Carlos A, Thomas T, Ghaby K, Fathi S, Sharma M, Nguyen NK, Farmwald M, Blachowicz L, Alcyone E, Harter K, Yu S, Pillai KS, Roux B and Moellering RE, 2026, Molecular Dynamics-Guided Design and Chemoproteomic Profiling of Covalent Kinase Activity Probes., Journal of the American Chemical Society, 148:12641-12654 

Ghaby K and Roux B, 2025, Kinetic Modeling of Covalent Inhibition: Effects of Rapidly Fluctuating Intermediate States., Journal of chemical information and modeling, 65:8730-8739 *co-first-authors 

Barragan AM*, Ghaby K*, Pond MP and Roux B, 2024, Computational Investigation of the Covalent Inhibition Mechanism of Bruton's Tyrosine Kinase by Ibrutinib., Journal of chemical information and modeling, 64:3488-3502. *co-first-authors 

Krahn AH, Pantazopoulou A, Austin J, Johnson N, Lee-Smith CF and Glick BS, 2025, COPI-dependent intra-Golgi recycling at an intermediate stage of cisternal maturation., 677526 bioRxiv 677526 [Preprint] 

Shangguan J and Rock RS, 2025, Quantifying Intracellular Distributions of HaloTagLabeled Proteins With SDS-PAGE and Epifluorescence Microscopy., Bioprotocol,15:e5391 

Shangguan J and Rock RS, 2024, Hundreds of myosin 10s are pushed to the tips of filopodia and could cause traffic jams on actin., eLife, 12

Lin X, Molina AV, Shangguan J, Chen R and Sosnick TR, 2025, Practical Tips for the Application of HDX-MS to Membrane Proteins, Biomolecular Condensates, and Weak Protein Binders., Journal of the American Society for Mass Spectrometry,36:1575-1587 

Chen R, Glauninger H, Kahan DN, Shangguan J, Sachleben JR, Riback JA, Drummond DA and Sosnick TR, 2024, HDX-MS finds that partial unfolding with sequential domain activation controls condensation of a cellular stress marker., Proceedings of the National Academy of Sciences of the United States of America,121:e2321606121

Wang KT, Tsai FY, Chen YC, Judy CP, Weathers IE, Özkan E and Adler CE, 2026, RoboA reinforces planarian stem cell fate through FoxA and Anosmin1a., Nature communications, 17

Priest JM, Zhang R, Olechwier AM, Caspi-Lebovic AB, Ashley J, Aher V, Carrillo RA and Özkan E, 2025, Structural insights into wiring specificity in the neuromuscular system through the Beat-Side complex., bioRxiv 656487 [Preprint]

Lobb-Rabe M, Nawrocka WI, Zhang R, Ashley J, Carrillo RA and Özkan E, 2024, Neuronal Wiring Receptors Dprs and DIPs Are GPI Anchored and This Modification Contributes to Their Cell Surface Organization., eNeuro, 1

Wang Y, Zhang R, Huang S, Valverde PTT, Lobb-Rabe M, Ashley J, Venkatasubramanian L and Carrillo RA, 2023, Glial Draper signaling triggers crossneuron plasticity in bystander neurons after neuronal cell death in Drosophila., Nature communications, 14:4452

Lobb-Rabe M, DeLong K, Salazar RJ, Zhang R, Wang Y and Carrillo RA, 2022, Dpr10and Nocte are required for Drosophila motor axon pathfinding., Neural development, 17:10

García-Bayona L, Said N, Coyne MJ, Flores K, Elmekki NM, Sheahan ML, Camacho AG, Hutt K, Yildiz FH, Kovács ÁT, Waldor MK and Comstock LE, 2024, A pervasive large conjugative plasmid mediates multispecies biofilm formation in the intestinal microbiota increasing resilience to perturbations., bioRxiv 590671 [Preprint]

Elmekki NM, Coyne MJ, Flores K, García-Bayona L, Comstock LE. High-throughput analyses of Phocaeicola vulgatus reveal fitness determinants for gut colonization and during colitis. Gut Microbes. 2026 Dec 31;18(1):2661410. doi: 10.1080/19490976.2026.2661410. Epub 2026 Apr 23. PMID: 42026761; PMCID: PMC13114119.

Duzdevich D, Nisler C, Petkowski JJ, Bains W, Kaminsky CK, Szostak JW and Seager S, 2025, Simple Lipids Form Stable Higher-Order Structures in Concentrated Sulfuric Acid., Astrobiology, 25:270-28

Rizzo HE, Zhang AL and Gardel ML, 2024, Mechanochemical control systems regulating animal cell size., Current opinion in cell biology, 91:10244