Training Faculty:
- Adams, Erin: Structure and biochemistry of proteins involved in immunological recognition
- Arac-Ozkan, Demet: Understanding the mechanism by which adhesion-type G protein- coupled receptors (GPCRs) function in the brain
- Bishop, Douglas: Meiotic recombination and homology-directed repair
- Carrillo, Robert: To understand the molecules and developmental programs that regulate neuronal development and wiring
- Concepcion, Axel: How membrane proteins and ion channels regulate the function of immune cells in health and disease
- Chen, Jueqi: Innate immune signaling pathways and their crosstalk with pathogenic microorganisms
- Chervonsky, Alexander: Pathogenesis of autoimmune diseases; how T cells activate in disease pathogenesis, home and destroy target organs
- Drummond, Allan: Cellular stress response focusing on formation and dissolution of large assemblies of proteins and RNA
- Du, Wei: RB family proteins in Drosophila and dissection of the RB pathway through genetic screens
- Fehon, Richard: Regulation of epithelial polarity and proliferation during development
- Fei, Jingyi: Quantitative biology of RNA; single molecule microscopy and super-resolution imaging
- Gardel, Margaret: Cell adhesion and migration; cytoskeletal dynamics; cell and tissue mechanics
- Glick, Benjamin: Biogenesis of secretory pathway organelles, and directed evolution of fluorescent proteins
- Glotzer, Michael: Molecular mechanisms of animal cytokinesis, and optogenetic tool development
- Golovkina, Tatyana: Retrovirus-host interactions; anti-virus immune response; resistance to retroviral infection; microbiota on viral infections
- Greenberg, Jean: Plant defense mechanisms and bacterial pathogenesis
- Heckscher, Ellie: Development and function of motor circuits for a mechanistic understanding of the genetic basis of behavior
- Horne-Badovinac, Sally: Epithelial morphogenesis and organ shape
- Keenan, Robert: Structural biology; biogenesis and quality control of membrane proteins
- Kossiakoff, Anthony: Structural biology, antibody engineering and receptormediated drug delivery
- Kovar, David: Biochemical mechanisms of actin filament assembly
- Kratsios, Paschalis: Motor neuron development and disease
- Kron, Stephen: Checkpoints, mitosis and cyclin-dependent kinases; technology for proteomics, drug discovery and systems biology
- Kronforst, Marcus: Integrative genomics, population genetics, molecular and developmental biology, animal behavior, and field work
- Lee, Heng-Chi: Small RNAs-medicated epigenetic regulation & genome surveillance
- Light, Sam: The relationship between microbial metabolism and healthy/diseased states of the gut microbiota and exploiting these insights in the development of targeted therapies
- Mendoza, Juan: Structure-based engineering of cytokines
- Mimee, Mark: Synthetic biology to engineer the microbiome and exploring modification of commensal bacteria and bacteriophage for diagnostic and therapeutic applications
- Missiakas, Dominique: Protein secretion pathways of Staphylococcus aureus and Bacillus anthracis and their contribution to virulence
- Moskowitz, Ivan: Genetic, genomic and molecular study of gene regulatory networks in cardiac biology
- Mukherjee, Sampriti: How bacteria process sensory inputs to control individual and collective behaviors
- Munro, Ed: Cytoskeletal dynamics, cell polarity and tissue morphogenesis
- Ozkan, Egin: Understanding the development and functioning of the nervous system through structural biology and biochemistry
- Pan, Tao: Functional genomics of tRNA; RNA epigenetics; RNA folding
- Perozo, Eduardo: Structure and dynamics of ion channels and transporters
- Piccirilli, Joseph: Chemistry/biochemistry of nucleic acids; structure and mechanism of ribozymes; bioorganic chemistry
- Pincus, David: System mechanics of cellular stress responses
- Prince, Victoria: Pattern formation along the primary body axis of the Zebrafish embryo and other teleosts
- Ragsdale, Clifton W.: Cellular and molecular control of brain nucleogenesis
- Randall, Glenn: Roles of hepatitis C virus (HCV) and Dengue virus host interactions in viral replication and pathogenesis
- Ranganathan, Rama: Design principles that underlie structure, function, and adaptation in biological systems at the atomic to cellular scale.
- Rebay, Ilaria: How signaling and transcription networks control cellular decision making, tissue-level patterning and morphogenesis
- Rice, Phoebe: Structural biology, biochemistry and microbiology of mobile DNA
- Riesenfeld, Samantha: Computational approaches to study the circuits that regulate gene expression and cellular function
- Rock, Ron: Molecular motors; cytoskeletal organization; single-molecule biophysics
- Roux, Benoit: Theoretical and computational studies of the structure, dynamics and function of biological macromolecular systems
- Rust, Michael: Experimental and computational approaches to circadian and other biological rhythms
- Ruthenburg, Alex: Chromatin biochemistry, biophysics and chemical biology
- Schmidt-Ott, Urs: Molecular and genetic basis for evolution of embryo polarity, patterning and morphogenesis in Dipterans
- Sosnick, Tobin: Protein and RNA/ribozyme folding; biological structure and thermodynamics as basis for understanding function
- Staley, Jonathan: Pre-mRNA splicing; non-coding RNA function, mechanism and regulation
- Szostak, Jack: Biochemistry; synthetic biology and bioengineering
- Tang, Wei-Jen: cAMP-mediated signal transduction; anthrax pathogenesis
- Thornton, Joe: Functional evolutionary genetics
- Turkewitz, Aaron: Secretory granules; exocytosis and endocytosis; evolution of membrane traffic
- Wu, Xiaoyang: Role of cytoskeletal dynamics in transmitting the niche signals to regulate skin somatic stem cell activity and functions
- Zhao, Minglei: CryoEM and crystallography of macromolecules involved in protein aggregation and neurodegeneration