Jeffrey Hubbell

Delivery of butyrate to the lower gut by polymeric micelles prolongs survival of distal skin allografts.
Delivery of butyrate to the lower gut by polymeric micelles prolongs survival of distal skin allografts. Am J Transplant. 2024 Nov 18.
PMID: 39566659

Blocking antibodies against integrin-a3, -aM, and -aMß2 de-differentiate myofibroblasts, and improve lung fibrosis and kidney fibrosis.
Blocking antibodies against integrin-a3, -aM, and -aMß2 de-differentiate myofibroblasts, and improve lung fibrosis and kidney fibrosis. Sci Rep. 2024 09 16; 14(1):21623.
PMID: 39284829

Semaphorin 3A promotes the long-term persistence of human SVF-derived microvascular networks in engineered grafts.
Semaphorin 3A promotes the long-term persistence of human SVF-derived microvascular networks in engineered grafts. Front Bioeng Biotechnol. 2024; 12:1396450.
PMID: 39234267

Injectable butyrate-prodrug micelles induce long-acting immune modulation and prevent autoimmune arthritis in mice.
Injectable butyrate-prodrug micelles induce long-acting immune modulation and prevent autoimmune arthritis in mice. J Control Release. 2024 Aug; 372:281-294.
PMID: 38876359

Cysteine-binding adjuvant enhances survival and promotes immune function in a murine model of acute myeloid leukemia.
Cysteine-binding adjuvant enhances survival and promotes immune function in a murine model of acute myeloid leukemia. Blood Adv. 2024 04 09; 8(7):1747-1759.
PMID: 38324726

A serine-conjugated butyrate prodrug with high oral bioavailability suppresses autoimmune arthritis and neuroinflammation in mice.
A serine-conjugated butyrate prodrug with high oral bioavailability suppresses autoimmune arthritis and neuroinflammation in mice. Nat Biomed Eng. 2024 May; 8(5):611-627.
PMID: 38561491

LDL-Binding IL-10 Reduces Vascular Inflammation in Atherosclerotic Mice.
LDL-Binding IL-10 Reduces Vascular Inflammation in Atherosclerotic Mice. bioRxiv. 2024 Mar 06.
PMID: 38496521

Therapeutic synthetic and natural materials for immunoengineering.
Therapeutic synthetic and natural materials for immunoengineering. Chem Soc Rev. 2024 Feb 19; 53(4):1789-1822.
PMID: 38170619

Immunoengineering a Future of Molecular, Material, and Cellular Therapeutics.
Immunoengineering a Future of Molecular, Material, and Cellular Therapeutics. J Immunol. 2024 01 15; 212(2):167-168.
PMID: 38166250

Synthetically mannosylated antigens induce antigen-specific humoral tolerance and reduce anti-drug antibody responses to immunogenic biologics.
Synthetically mannosylated antigens induce antigen-specific humoral tolerance and reduce anti-drug antibody responses to immunogenic biologics. Cell Rep Med. 2024 01 16; 5(1):101345.
PMID: 38128533

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