Immunology

The Committee on Immunology offers a graduate program of study leading to the Ph.D. in Immunology, as well as an undergraduate specialization in Immunology, and courses for medical students. The program provides multidisciplinary training in all aspects of Immunology that includes a core immunology curriculum and several advanced graduate level courses in specialized areas. The training also integrates the basic biological sciences with the clinical sciences in an effort to develop new immunological approaches to the diagnosis and treatment of various immune diseases and cancer. Approximately thirty students are enrolled in the Ph.D. program, which has won training grant support from the NIH continuously for over thirty-five years.

Faculty in Immunology

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39 Faculty 32 Current Students NIH Supported

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2004

Cathryn Nagler: discovered links between intestinal bacteria and immunology

In 2004 Cathryn Nagler, the Bunning Family Professor in the Pritzker School of Molecular Engineering and the Department of Pathology, was one of the first scientists to discover the link between intestinal bacteria and immunology. In 2014, Nagler discovered that Clostridia, a class of gut bacteria, protects against food allergies. Her research group is now working to find a treatment for food allergies via a microbiome-based treatment.

1965

Donald F. Steiner: discovered proinsulin, advancing diabetes treatment

Biochemist Donald F. Steiner, SM’56, MD’56, discovered proinsulin, the first “pro-hormone” and precursor to insulin. The 1965 finding led to the synthetic production of human insulin, markedly improving therapy for diabetes sufferers, and laid the groundwork for improved understanding of how other proteins in the body are made.

1977

Eugene Goldwasser: discovered source of red blood cell formation

Biochemist Eugene Goldwasser isolated erythropoietin (EPO), the hormone behind red blood cell formation. The 1977 discovery led to the development of the first blockbuster drug of the biotech age, which has since treated millions with anemia.

1949

Leon O. Jacobson: performed the first bone marrow transplant

In 1949, medical researcher Leon O. Jacobson, MD’39, performed the first bone marrow transplant. He discovered he could save a mouse whose bone marrow and spleen had been destroyed by transplanting donated spleen tissue into the mouse. The procedure now helps thousands of patients with cancer and other diseases each year.

Leon O. Jacobson, the Joseph Regenstein Professor in Medicine, in his laboratory

1930s

Joseph B. Kirsner: transformed the field of gastroenterology

Gastroenterologist Joseph B. Kirsner joined UChicago in 1935, then pioneered modern understanding and treatment of inflammatory bowel disease He was one of the first to show the link between ulcerative colitis and increased risk of colon cancer, introduced guidelines for how doctors should care for patients, and helped found the American Gastroenterological Association, the American Society for Gastrointestinal Endoscopy, and the American Association for the Study of Liver Diseases.

Immunology

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