Predoctoral Training Program in Chemistry and Biology (T32 GM08720)

Program Directors: Yamuna Krishnan and Joseph A. Piccirilli

Administrator: Shani Charles
Phone: 4-6719

Openings: 6 Predoctoral, 0 Postdoctoral

The Predoctoral Training Program in Chemistry & Biology, supported through a grant of the National Institutes of Health (T32 GM008720), is one of the few interdivisional, interdisciplinary predoctoral training program at The University of Chicago. Students are admitted to the program from both the Division of Physical Sciences and the Division of Biological Sciences. Students fulfill simultaneously the requirements of the CBI program and the requirements of the program of graduate study leading to the Ph. D. degree in which they are enrolled. The main objective of the program is cross-training of students at the interface of the chemical and biological sciences with a mechanistic and synthetic focus. This goal is achieved through (1) satisfactory completion the Chemical Biology course sequence or a course offered from the department of the other scientific discipline as electives; (2) an elective research rotation under the guidance of a participating faculty member; (3) participation in a series of monthly meetings throughout the academic year designated as Advanced Chemical Tools in Biology (ACT-Bio) Lunch Seminar to gain acquaintance with theoretical concepts and methods. The broad scope of the interdisciplinary research interests of the faculty participating in the training program, strengthened through collaborative research projects and interactions, ensures a large variety of opportunities for meaningful cross-training experience.

The program offers a supportive environment for training of students in cutting-edge research at the interface of chemistry and biology.

Training Faculty:

  • Piccirilli, Joseph: Bioorganic - Chemical Biology
  • He, Chuan: Bioinorganic - Bioorganic - Catalysis - Chemical Biology
  • Dickinson, Bryan: Chemical Biology - Protein Engineering - Molecular Evolution
  • Keenan, Robert: Structural biology and directed evolution
  • Kossiakoff, Anthony: Structure and function of hormone-receptor interactions, enzyme-inhibitor interfaces, and synthetic proteins
  • Krishnan, Yamuna: Bioorganic Chemistry - Chemical Biology
  • Lee, Ka Yee Christina: Biophysical - Materials - Surface
  • Meredith, Stephen C.: Protein aggregation and amyloid fibril structure; peptide synthesis; lipoprotein structure.
  • Moellering, Raymond: Bioorganic - Chemical Biology - Proteomics
  • Ozkan, Engin: Proteomics, Structural Biology
  • Pan, Tao: NA genomics, RNA epigenetics, RNA folding
  • Rawal, Viresh: Asymmetric Catalysis - Organic Synthesis
  • Rice, Phoebe: Mechanisms of DNA recombination and protein- DNA recognition, combining the tools of biochemistry and x-ray crystallography.
  • Rock, Ronald S.: Molecular motors; cytoskeletal organization; single-molecule biophysics
  • Ruthenburg, Alexander: How post-translational modifications and noncoding RNA can control chromatin structure
  • Schwartz, Nancy B.: Transcriptional control of ECM expression during chondrogenesis and neurogenesis; regulation of sulfate activation; skeletal dysplasias.
  • Snyder, Scott: Chemical Biology; Organic Chemistry
  • Tang, Wei-Jen: Molecular basis of protein-protein and protein-ligand interaction
  • Tang, Weixin: Chemical Biology; Biophysics; Organic Chemistry
  • Tian, Bozhi: Biophysical - Materials - Nonoscale - Inorganic
  • Zhao, Minglei:  AAA+ ATPase, p97, Ubiquitination
  • Zhao, Yingming: Protein post-translationa lmodifications; functional characterization of protein post-translational modifications; mass spectrometry; proteomics
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