Program Director: Gokhan Mutlu and Yun Fang
Administrator: Juanita Tyler
Phone: 2-6790
Fax: 2-4736
Openings: 0 Predoctoral, 10 Postdoctoral
The objective of this research training program for Ph.D. or M.D. trainees is to produce scientists whose basic investigations in cell and molecular biology elucidate the pathophysiology of human respiratory disease and critical illness. The program focuses primarily on Airway Biology and on Endothelial Cell Biology. Areas of training include: cell and molecular biology of airway and vascular tissue components; mechanisms of inflammation; tissue remodeling and growth; immunology; and organ physiology. Formal coursework, research presentations, and clinical exposure, coupled with laboratory investigation, provide broad experience designed to facilitate transition to the trainees’ independent research careers.
Training Faculty:
- Mutlu, Gokhan: Mechanisms of lung injury, repair and fibrosis
- Fang, Yun: Non-coding RANs in Vascular Pathophysiology
- Adams, Erin: Molecular Immunology
- Adegunsoye, Ayodeji: Impact of telomere lengths in Pulmonary Fibrosis
- Alegre, Maria-Luisa: Induction and antagonism of transplantation tolerance
- Alverdy, John: Life-threatening infections following trauma, major surgery, and during critical illness
- Bendelac, Albert: The development and function of innate lymphocytes
- Chang, Eugene B.: Host-microbe interactions in immune development and metabolic regulation
- Chong, Anita: Immunological tolerance and humoral immunity in allogeneic transplantation
- Clark, Marcus: Immunity in the pathogenesis of human autoimmune diseases
- Dulin, Nickolai: Signaling mechanisms of myofibroblast differentiation and pulmonary fibrosis
- Gilad, Yoav: Human genetics, gene regulation, and genome biology
- Grossman, Robert: Informatics and Data Intensive Computing
- Huang, Elbert: Health services and translational research questions at the intersection of aging, diabetes, and health economics
- Hubbell, Jeffrey: Molecular bioengineering, regenerative medicine, and engineering immunity
- Konetzka, R. Tamara: Health economics, long-term care; effects of financing and market structure on quality of care; Medicare and Medicaid policy; health workforce issues.
- Kress, John: Optimizing outcomes in mechanically ventilated ICU patients
- Meltzer, David: Health economics and public policy; theoretical foundations of medical cost-effectiveness analysis; determinants of the cost/quality of hospital care
- Nagler, Cathryn: Mechanisms governing tolerance to dietary antigens and the potential immunomodulato ry features of this route of antigen administration
- Ober, Carole: Genetic, epigenetic, and genomic studies of asthma
- Olopade, Christopher: Asthma-Environment and genetics; Global Health: Household air pollution, health and epigenetics
- Patel, Bhakti: Identify patient care interventions that mitigate or prevent long-term complications of critical illness
- Prabhakar, Nanduri: Hypoxic sensing by carotid body chemoreceptors and autonomic functions
- Ross, Lainie Friedman: Research ethics; ethical and policy issues in Cystic Fibrosis newborn screening
- Rzhetsky, Andrey: Modeling of genetic data in the context of molecular networks, with focus on autism, bipolar disorder, schizophrenia, and Alzheimer’s disease
- Solway, Julian: Airway Smooth Muscle Asthma; Translational Medicine
- Strek, Mary: Diagnosis and treatment of chronic lung disease
- Swartz, Melody: Lymphatic vessels and their transport functions in inflammation and immunity
- Thompson, Emma: Genetics of airway hyper-responsiveness
- Tasali, Esra: Role of insufficient sleep in the development of metabolic diseases such as diabetes and obesity
- Tay, Savas: Examining how signaling pathways control cellular decision- making
- White, Steven: Regulation of airway repair after injury