Research Training in Respiratory Biology (T32 HL07605)

Program DirectorAnne Sperling

Administrator: Juanita Tyler
Phone: 2-6790
Fax: 2-4736

Openings: 0 Predoctoral, 10 Postdoctoral

The objective of this research training program for Ph.D. or M.D. trainees is to produce scientists whose basic investigations in cell and molecular biology elucidate the pathophysiology of human respiratory disease and critical illness. The program focuses primarily on Airway Biology and on Endothelial Cell Biology. Areas of training include: cell and molecular biology of airway and vascular tissue components; mechanisms of inflammation; tissue remodeling and growth; immunology; and organ physiology. Formal coursework, research presentations, and clinical exposure, coupled with laboratory investigation, provide broad experience designed to facilitate transition to the trainees’ independent research careers.

Training Faculty:

  • Sperling, Anne: The immunology of lung diseases
  • Solway, Julian: Airway Smooth Muscle Asthma; Translational Medicine
  • Alegre, Maria-Luisa: Induction and antagonism of transplantation tolerance
  • Bendelac, Albert: The development and function of innate lymphocytes
  • Beyer, Eric: Intercellular communication as mediated by gap junctions
  • Birukov, Konstantin: Molecular mechanisms of lung injury and repair
  • Birukova, Anna: Molecular mechanisms of acute lung injury and cytoskeletal mechanisms of endothelial barrier regulation
  • Chang, Eugene B.: Host-microbe interactions in immune development and metabolic regulation
  • Chong, Anita: Immunological tolerance and humoral immunity in allogeneic transplantation
  • Churpek, Matthew M.: Predicting and preventing in-hospital cardiac arrest
  • Clark, Marcus: Immunity in the pathogenesis of human autoimmune diseases
  • Dulin, Nickolai: Signaling mechanisms of myofibroblast differentiation and pulmonary fibrosis
  • Edelson, Dana: In-hospital cardiac arrest
  • Fang, Yun: Non-coding RANs in Vascular Pathophysiology
  • Garrity, Edward: Mechanisms of development of obliterative bronchiolitis; Immunosuppression for lung transplantation; Ethical issues in transplantation
  • Hall, Jesse B.: Pathophysiology of Respiratory and Circulatory Failure and Outcomes of Critical Illness
  • Konetzka, Rita Tamara: Health economics, long-term care; effects of financing and market structure on quality of care; Medicare and Medicaid policy; health workforce issues.
  • Kress, John: Optimizing outcomes in mechanically ventilated ICU patients
  • Meltzer, David: Health economics and public policy; theoretical foundations of medical cost-effectiveness analysis; determinants of the cost/quality of hospital care
  • Mutlu, Gokhan:  Mechanisms of lung injury, repair and fibrosis
  • Nagler, Cathryn: Regulation of allergic responses to food by the commensal microbiota
  • Noth, Imre: Genetics and development of genomic biomarkers in IPF
  • Ober, Carole: Genetic, epigenetic, and genomic studies of asthma
  • Olopade, Christopher: Asthma-Environment and genetics; Global Health: Household air pollution, health and epigenetics
  • Olopade, Olufunmilayo: Breast cancer; cancer risk assessment; cancer prevention
  • Prabhakar, Nanduri: Hypoxic sensing by carotid body chemoreceptors and autonomic functions
  • Press, Valerie: Addressing barriers to self-management of chronic diseases
  • Ross, Lainie Friedman: Research ethics; ethical and policy issues in Cystic Fibrosis newborn screening
  • Singleton, Patrick: Signal transduction of cell adhesion and migration
  • Strek, Mary: Diagnosis and treatment of chronic lung disease
  • Swartz, Melody: Lymphatic vessels and their transport functions in inflammation and immunity
  • Thompson, Emma: Genetics of airway hyper-responsiveness 
  • Vij, Rekha: Autoimmune Interstitial Lung Diseases
  • White, Steven: Regulation of airway repair after injury
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