Ada Weinstock, PhD

Assistant Professor of Medicine
Committee on Immunology
Committee on Molecular Metabolism and Nutrition
Research and Scholarly Interests: Hematopoietic Progenitor Cell, Immunometabolism, Macrophages, Resolution of Inflammation, Weight cycling, Weight Loss
Websites: Weinstock lab, Research Network Profile
Contact: adaweinstock@uchicago.edu
Graduate Programs: Immunology, Molecular Metabolism and Nutrition, UChicago Biosciences

Dr. Weinstock trained in the Weizmann Institute of Science in Israel and NYU School of Medicine, where she was trained in immunology, stem cells and molecular biology. Her group studies how weight loss cures obesity-related inflammation, and why weight cycling worsens obesity complications. They are focused on macrophages that resolve inflammation in weight loss and how metabolic cues influence hematopoietic stem cells to regulate systemic inflammation.

Dr. Weinstock is passionate about mentoring and helping academic trainees to find their desired careers.

Interferon-sensitized hematopoietic progenitors dynamically alter organismal immunity.
Interferon-sensitized hematopoietic progenitors dynamically alter organismal immunity. bioRxiv. 2024 Apr 28.
PMID: 38712060

Macrophage-to-endothelial cell crosstalk by the cholesterol metabolite 27HC promotes atherosclerosis in male mice.
Macrophage-to-endothelial cell crosstalk by the cholesterol metabolite 27HC promotes atherosclerosis in male mice. Nat Commun. 2023 07 25; 14(1):4101.
PMID: 37491347

The diverse roles of macrophages in metabolic inflammation and its resolution.
The diverse roles of macrophages in metabolic inflammation and its resolution. Front Cell Dev Biol. 2023; 11:1147434.
PMID: 36994095

Staphylococcus aureus induces a muted host response in human blood that blunts the recruitment of neutrophils.
Staphylococcus aureus induces a muted host response in human blood that blunts the recruitment of neutrophils. Proc Natl Acad Sci U S A. 2022 08 02; 119(31):e2123017119.
PMID: 35881802

Wnt signaling enhances macrophage responses to IL-4 and promotes resolution of atherosclerosis.
Wnt signaling enhances macrophage responses to IL-4 and promotes resolution of atherosclerosis. Elife. 2021 03 15; 10.
PMID: 33720008

Platelet-conditioned media induces an anti-inflammatory macrophage phenotype through EP4.
Platelet-conditioned media induces an anti-inflammatory macrophage phenotype through EP4. J Thromb Haemost. 2021 02; 19(2):562-573.
PMID: 33171016

Leukocyte Heterogeneity in Adipose Tissue, Including in Obesity.
Leukocyte Heterogeneity in Adipose Tissue, Including in Obesity. Circ Res. 2020 05 22; 126(11):1590-1612.
PMID: 32437300

Regulatory T Cells License Macrophage Pro-Resolving Functions During Atherosclerosis Regression.
Regulatory T Cells License Macrophage Pro-Resolving Functions During Atherosclerosis Regression. Circ Res. 2020 07 17; 127(3):335-353.
PMID: 32336197

Tamoxifen activity against Plasmodium in vitro and in mice.
Tamoxifen activity against Plasmodium in vitro and in mice. Malar J. 2019 Nov 27; 18(1):378.
PMID: 31775753

Netrin-1 Alters Adipose Tissue Macrophage Fate and Function in Obesity.
Netrin-1 Alters Adipose Tissue Macrophage Fate and Function in Obesity. Immunometabolism. 2019; 1(2).
PMID: 31428465
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Ada Weinstock, PhD

Publications