Raymond E. Moellering

Direct inhibition of tumor hypoxia response with synthetic transcriptional repressors.
Direct inhibition of tumor hypoxia response with synthetic transcriptional repressors. Nat Chem Biol. 2024 Aug 30.
PMID: 39215099

PARK7 Catalyzes Stereospecific Detoxification of Methylglyoxal Consistent with Glyoxalase and Not Deglycase Function.
PARK7 Catalyzes Stereospecific Detoxification of Methylglyoxal Consistent with Glyoxalase and Not Deglycase Function. Biochemistry. 2023 11 07; 62(21):3126-3133.
PMID: 37884446

LKB1-Dependent Regulation of TPI1 Creates a Divergent Metabolic Liability between Human and Mouse Lung Adenocarcinoma.
LKB1-Dependent Regulation of TPI1 Creates a Divergent Metabolic Liability between Human and Mouse Lung Adenocarcinoma. Cancer Discov. 2023 04 03; 13(4):1002-1025.
PMID: 36715544

Spatial Chemoproteomics for Mapping the Active Proteome.
Spatial Chemoproteomics for Mapping the Active Proteome. Isr J Chem. 2023 Mar; 63(3-4).
PMID: 38046285

Widespread, Reversible Cysteine Modification by Methylglyoxal Regulates Metabolic Enzyme Function.
Widespread, Reversible Cysteine Modification by Methylglyoxal Regulates Metabolic Enzyme Function. ACS Chem Biol. 2023 01 20; 18(1):91-101.
PMID: 36562291

Targeting MYC with modular synthetic transcriptional repressors derived from bHLH DNA-binding domains.
Targeting MYC with modular synthetic transcriptional repressors derived from bHLH DNA-binding domains. Nat Biotechnol. 2023 04; 41(4):541-551.
PMID: 36302987

SARS-CoV-2 Diverges from Other Betacoronaviruses in Only Partially Activating the IRE1a/XBP1 Endoplasmic Reticulum Stress Pathway in Human Lung-Derived Cells.
SARS-CoV-2 Diverges from Other Betacoronaviruses in Only Partially Activating the IRE1a/XBP1 Endoplasmic Reticulum Stress Pathway in Human Lung-Derived Cells. mBio. 2022 10 26; 13(5):e0241522.
PMID: 36125275

SARS-CoV-2 diverges from other betacoronaviruses in only partially activating the IRE1a/XBP1 ER stress pathway in human lung-derived cells.
SARS-CoV-2 diverges from other betacoronaviruses in only partially activating the IRE1a/XBP1 ER stress pathway in human lung-derived cells. bioRxiv. 2022 Jun 13.
PMID: 35821981

Diels-Alder Cycloadditions for Peptide Macrocycle Formation.
Diels-Alder Cycloadditions for Peptide Macrocycle Formation. Methods Mol Biol. 2022; 2371:159-174.
PMID: 34596848

Methylglyoxal Forms Diverse Mercaptomethylimidazole Crosslinks with Thiol and Guanidine Pairs in Endogenous Metabolites and Proteins.
Methylglyoxal Forms Diverse Mercaptomethylimidazole Crosslinks with Thiol and Guanidine Pairs in Endogenous Metabolites and Proteins. ACS Chem Biol. 2021 11 19; 16(11):2453-2461.
PMID: 34581579

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