Graduate Training in Growth and Development (T32 HD07009)

Program DirectorNancy Schwartz

Administrator: Laurie Risner
Phone: 2-4722
Fax: 2-9234

Openings: 10 MD/PhD, 0 Predoctoral, 0 Postdoctoral

This is an integrated training program leading to both the M.D. and Ph.D. degrees. Students are considered for the program after they have completed one or in most cases two years of medical studies. Although not supported by the program during these pre-clinical years, students usually acquire relevant laboratory experience, fulfill some graduate course requirements and seek out a research sponsor and graduate degree unit in anticipation of their application to the program. If selected, the trainee may receive up to five years of support, which generally encompasses part of the Ph.D. phase and the remainder of the M.D. training (the two clinical years). A wide variety of Ph.D. degree-granting units are available to trainees, including: Biochemistry and Molecular Biology; Developmental Biology; Genetics; Immunology; Molecular Genetics and Cell Biology; Molecular Pathogenesis; and Neurobiology.

Training Faculty:

  • Schwartz, NancyRole of glycoconjugates in the developing limb and brain
  • Alegre, Maria-Luisa: Mechanisms of TCell inhibition and induction of tolerance for type 1 diabetes therapies
  • Awad, Issam:  Molecular mechanisms, biomarkers and therapeutic targets in cavernous angiomas (cerebral vascular malformations) and the pathobiology of brain hemorrhage
  • Clark, MarcusB Cell Development and Activation
  • Cunningham, John: Biology and therapy of hemoglobinopathies, the molecular mechanisms underpinning hematopoiesis and the development of the leukemia stem cell
  • de Jong, JillHematopoietic stem cells and understanding the genes that can cause leukemia
  • Gajewski, ThomasMolecular and cellular regulation of T lymphocyte activation and differentiation
  • Godley, LucyEpigenetic changes that alter chromatin structure and regulate gene transcription
  • Gomez, ChristopherMechanism of neurological disease, with a focus on genetic mutations
  • Greene, GeoffreyRegulation of development, differentiation and/or cellular proliferation, and survival by female steroid hormones
  • Grove, ElizabethMechanisms that drive early brain development
  • He, Chuan: Chemical biology, nucleic acid chemistry and biology, epigenetics, and bioinorganic chemistry
  • Kraig, RichardPhysical, mental and social activities that lessen impact of neurological development and disease
  • LaBelle, JamesCell death regulatory mechanisms in resistant hematopoietic disorders
  • Meredith, StephenMechanism of protein aggregation, and structure of amyloid fibrils
  • Moskowitz, IvanMolecular pathways that dictate cardiac morphogenesis and cis morphogenesis during development
  • Ober, CaroleIdentify genes that influence complex phenotypes, their evolutionary history, how variation influences function
  • Philipson, LouisRelationship and dysfunction of ion channels, intracellular Ca2+, insulin secretion in pancreatic ß-cells and diabetes mellitus
  • Romero, Iris: Identifying novel interventions for ovarian cancer prevention and treatment
  • Ross, Callum: Biomechanics of the head, with special emphasis on the feeding apparatus
  • Ruthenburg, Alexander: Elucidation of molecular mechanisms underlying management chromatin, the physiological form of the genome
  • Stephens, Matthew: Statistical and population geneticist
  • Tay, Savas
  • Volchenboum, Samuel L.: Using bioinformatics to study complex diseases, especially pediatric blood disorders
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