Graduate Training in Growth and Development (T32 HD07009)

Program DirectorNancy Schwartz

Administrator: Laurie Risner
Phone: 2-4722
Fax: 2-9234

Openings: 10 MD/PhD, 0 Predoctoral, 0 Postdoctoral

This is an integrated training program leading to both the M.D. and Ph.D. degrees. Students are considered for the program after they have completed one or in most cases two years of medical studies. Although not supported by the program during these pre-clinical years, students usually acquire relevant laboratory experience, fulfill some graduate course requirements and seek out a research sponsor and graduate degree unit in anticipation of their application to the program. If selected, the trainee may receive up to five years of support, which generally encompasses part of the Ph.D. phase and the remainder of the M.D. training (the two clinical years). A wide variety of Ph.D. degree-granting units are available to trainees, including: Biochemistry and Molecular Biology; Developmental Biology; Genetics; Immunology; Molecular Genetics and Cell Biology; Molecular Pathogenesis; and Neurobiology.

Training Faculty:

  • Schwartz, Nancy: Role of glycoconjugates in the developing limb and brain
  • Alegre, Maria-Luisa: Mechanisms of TCell inhibition and induction of tolerance for type 1 diabetes therapies
  • Ardelt, Agnieszka: Traumatic brain injuries, hydrocephalus, status epilepticus, myasthnia gravis crisis, Guillan-Barre syndrome, meningitis
  • Clark, Marcus: B Cell Development and Activation
  • de Jong, Jill: Hematopoietic stem cells and understanding the genes that can cause leukemia
  • Gajewski, Thomas: Molecular and cellular regulation of T lymphocyte activation and differentiation
  • Godley, Lucy: Epigenetic changes that alter chromatin structure and regulate gene transcription
  • Gomez, Christopher: Mechanism of neurological disease, with a focus on genetic mutations
  • Gozal, David: Pediatric sleep disorders, such as childhood obstructive sleep apnea and sudden infant death syndrome (SIDS)
  • Greeley, Siri: Classification of the diabetes types, monogenic diabetes caused by single gene mutations
  • Greene, Geoffrey: Regulation of development, differentiation and/or cellular proliferation, and survival by female steroid hormones
  • Grove, Elizabeth: Mechanisms that drive early brain development
  • Kraig, Richard: Physical, mental and social activities that lessen impact of neurological development and disease
  • LaBelle, James: Cell death regulatory mechanisms in resistant hematopoietic disorders
  • Marcuccilli, Charles: Identifying the neurons that burst in epilepsy and the cellular properties of epileptogenesis
  • Meredith, Stephen: Mechanism of protein aggregation, and structure of amyloid fibrils
  • Moscovitz, Ivan: Molecular pathways that dictate cardiac morphogenesis and cis morphogenesis during development
  • Ober, Carole: Identify genes that influence complex phenotypes, their evolutionary history, how variation influences function
  • Philipson, Louis: Relationship and dysfunction of ion channels, intracellular Ca2+, insulin secretion in pancreatic ß-cells and diabetes mellitus
  • Ross, Callum: Biomechanics of the head, with special emphasis on the feeding apparatus
  • Schneewind, Olaf: Mechanisms and strategies whereby pathogenic bacteria cause human disease
  • Schreiber, Hans: Fundamental mechanisms that govern the interaction of cancer cells with the immune system
  • Stephens, Matthew: Statistical and population geneticist
  • Volchenboum, Samuel L.: Using bioinformatics to study complex diseases, especially pediatric blood disorders
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