Training Grant Administration

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1890s

Henry Chandler Cowles: led formational work in the study of ecology

Botanist Henry Chandler Cowles’s study of ecological succession in the Indiana Dunes along the southern shore of Lake Michigan in the late 1890s opened a new field of inquiry in the natural sciences: ecology. The investigation of a changing natural landscape carries increasing importance amid growing concerns about our environment.

1958

Elwood Jensen and Eugene Desombre: discovered the hormone-cancer mechanism

Building on the work of cancer researcher Charles B. Huggins, Elwood Jensen and fellow medical researcher Eugene Desombre identified the precise mechanism through which hormones drive cancer—by binding to a receptor protein in cells. The 1958 finding opened a new therapeutic front in breast cancer, leading to targeted treatments credited with saving many lives each year.

1930s

Joseph B. Kirsner: transformed the field of gastroenterology

Gastroenterologist Joseph B. Kirsner joined UChicago in 1935, then pioneered modern understanding and treatment of inflammatory bowel disease He was one of the first to show the link between ulcerative colitis and increased risk of colon cancer, introduced guidelines for how doctors should care for patients, and helped found the American Gastroenterological Association, the American Society for Gastrointestinal Endoscopy, and the American Association for the Study of Liver Diseases.

1941

Charles B. Huggins: introduced hormonal treatment of cancer

In 1941, cancer researcher Charles B. Huggins treated patients suffering from advanced prostate cancer by removing the hormone the cancers needed to grow. Hormonal treatment has since become a mainstay of care for several types of cancer, including breast and gynecological cancers.

Nobel laureate Charles B. Huggins, the William B. Ogden Distinguished Service Professor in Surgery, working in his laboratory

1965

Donald F. Steiner: discovered proinsulin, advancing diabetes treatment

Biochemist Donald F. Steiner, SM’56, MD’56, discovered proinsulin, the first “pro-hormone” and precursor to insulin. The 1965 finding led to the synthetic production of human insulin, markedly improving therapy for diabetes sufferers, and laid the groundwork for improved understanding of how other proteins in the body are made.